for whom, Moderna, Pfizer, deadline

The booster vaccination (3rd dose) is strongly recommended for 12-17 year olds and adults. What is the deadline for doing this? With Pfizer or Moderna? After having the Covid? For who ? At what age ? What efficiency? What are the possible side effects ?

The immunity conferred by the anti-Covid vaccination decreases over time. This is why it is necessary to make a booster shotin other words a 3rd dose, in order to strengthen its immune system against the coronavirus and its variants. Who should do a booster vaccination? When to do it? What is a full vaccination schedule? Is it mandatory to keep your health pass? What deadline? What are the possible side effects ? Understand everything.

Who is affected by the booster shot?

People aged 12 and over can receive a booster shot by respecting a minimum period after their last injection or infection with Covid.

What is the deadline for doing a booster shot?

The vaccination booster must be done:

  • From 3 months for people aged 18 and more after the last dose of the initial regimen.

→ Persons vaccinated with Janssen must receive an additional injection from 4 weeks after their vaccination, then a booster dose as early as 3 months after the latter.
→ People who have had a Covid-19 infection and then a dose of Janssen are eligible for the booster dose from 4 weeks after their injection.

  • For people who had Covid after their Janssen injection, 2 situations:

If infection less than 15 days after the injection: people receive an additional dose of mRNA vaccine 4 weeks after infection. They are eligible for the booster vaccine from 3 months after this additional dose.

If infection more than 15 days after the injection: people do not need to complete their vaccination schedule with an additional dose. They are eligible for the booster from 3 months after infection.

→ People who have had Covid-19 more than 15 days after their additional dose do not need to take their booster dose unless they are traveling to a country where the booster dose is compulsory. In this case, they can do their booster dose as early as 3 months after their infection.

  • From 6 months after the last injection for minors aged 12 to 17.
  • For immunocompromised people, it is recommended to follow the advice of their healthcare professional as to the most suitable vaccination schedule.

One infection = one injection. So, if you contracted Covid-19 after your initial vaccination schedule, you do not need to do a booster dose. However, for people wishing to leave the national territory, the vaccination booster must be done to have a valid vaccination certificate.

L’Assurance Maladie has put the My Covid vaccine reminder service online, which allows you to:

  • to know from when you must take your booster dose against Covid-19
  • to know the expiry date of your vaccination pass if you do not send a reminder.

What is a complete vaccination schedule?

  • About the vaccine COVID-19 Vaccine Janssen, the initial scheme is complete 28 days after administration of a dose.
  • For other vaccines, the initial regimen is complete 7 days after administration of a 2nd dose. A Covid-19 infection is equivalent to the administration of one of these first 2 doses.

► To obtain a complete vaccination certificate with a QR Code, several options:

– During your vaccination appointment, the healthcare professional gives you a vaccination certificate with a QR code.

– Download it from the Health Insurance online service (Ameli) using your social security number (if you have one);

– Go to a health professional (doctor, pharmacist, nurse, midwife, etc.), with your vital card (if you have one) so that he can issue you a new one.

Where to receive your booster shot?

You can get vaccinated:

  • in a vaccination center ;
  • at a health professional :
  • in pharmacy,
  • at a doctora oral surgeona male nurse or a midwife,
  • in a laboratory of medical biology.

To call back, you can make an appointment on Doctolib, Maiia, Keldoc, Quick my Dose. People over 65 can be vaccinated without an appointment at any vaccination centre.

When should you do a vaccination reminder to keep your health pass?

Since March 14, the vaccination pass has been lifted. However, the health pass is still required in certain places, in particular in hospitals, retirement homes, establishments for disabled adults, nursing homes. Several cases:

► If you have between 12 and 17 years oldyou can receive a booster dose as soon as 6 months after your initial vaccination. This booster shot is recommendedbut it is not not mandatory as part of the health pass.

► If you have over 18 years and 1 monthyou can receive a booster dose as soon as 3 months after your initial vaccination, and within up to 4 monthsotherwise your sanitary pass will be deactivated.

► If you have had the Covid at least 3 months after your initial vaccination, you have no no need to receive a booster dose. You will be able to extend your pass with your positive test result (certificate of reinstatement).

Receive your vaccination booster to keep your health pass © My Covid tips

If you want to go on a trip abroad : the recovery certificate is not recognized by all countries, and a booster vaccination may be required.

– A serological test (or serology) does not dispense with a booster dose and does not take the place of a health pass.

When should you do a booster shot if you have had the Covid?

If you had Covid after your initial vaccination, you can use the QR code of your positive PCR or antigen test at least 11 days old (also called certificate of reinstatement) inasmuch as sanitary pass. Her period of validity depends on the time that elapsed between your vaccination and contamination.

Time of positive test Period of validity of the certificate of reinstatement
Less than 3 months after initial vaccination 4 months
More than 3 months after initial vaccination Unlimited

Who should take a 4th dose of vaccine?

Since March 14, 2022, people aged 80 and over as well as residents of nursing homes and USLDs are eligible for a second booster vaccination, from 3 months after the injection of the first booster, in accordance with the opinion of the Council for the orientation of the vaccine strategy of February 18, 2022. The same applies to immunocompromised people.

How effective is the booster vaccine?

The booster dose restores an immune response to the Omicron variant.

According to the opinion of the Scientific Council of December 16, 2021, the booster dose (2nd or 3rd dose) makes it possible to restore an immune response to the Omicron variant. It protects, probably at a good level, against the occurrence of severe and serious forms but only partially protects against infection with the Omicron variant. The first estimates of real-life vaccine efficacy have documented protection against symptomatic forms of infection with the Omicron variant of SARS-CoV-2 increasing from 80% 1-2 months to 34% 4 months after the second dose of a Pfizer vaccine, to rise to 75% two weeks after a booster dose. According to the Haute Autorité de Santé, the booster dose makes it possible to raise vaccine efficacy on cases of infection and severe forms. “The observed real-life efficacy data for a booster dose of the Comirnaty® vaccine given first in people 60 years of age or older vaccinated with two doses at least five months previously show a decrease the risk of infection by Covid-19 (…), 11.3 times lower cases of infections and cases of severe forms 19.5 times lower among people who had a booster dose than among those who did not. The effectiveness of the 3rd dose is observed in a short delay (very strong immunological response in a few days, clinically significant protection clearly shown from day 7) specified the Covid Scientific Council in an Opinion of November 22, 2021. The administration of a booster dose would also decrease the viral load and in fact, probably the contagiousness people developing an infection with SARS-CoV-2.

Vaccines from Pfizer and Moderna have received an extension of their marketing authorization for the recall, from the European Medicines Agency (EMA). Moderna obtained an extension of indication on October 25 for the administration of a booster dose of 50 mcg (half dose) in people aged 18 years and over. “Spikevax® (Moderna) and Comirnaty® from Pfizer are two safe and effective vaccines, but studies show a slight superiority of Spikevax® in terms of efficacy and lower risks of myocarditis for Comirnaty®, especially for people under the age of 30″ indicates the HAS in an Opinion of November 8, 2021. The HAS recommends as follows:

For those under 30: to do his booster dose with the Comirnaty® vaccine (Pfizer). “In the population under 30 years of age, the risk of myocarditis appears approximately 5 times lower for the Comirnaty® vaccine from Pfizer compared to the Spikevax® vaccine from Moderna (100 µg) in 12-29 year olds“, specifies the HAS in its press release.

For those over 30: to do their booster dose with the Pfizer or Moderna vaccine. “This is particularly interesting for people at risk of a severe form of Covid-19” notes the HAS which recommends the administration of a half-dose for the booster (50 µg of RNA instead of 100 in primary vaccination).

When an mRNA vaccine (Moderna and Pfizer) cannot be used, HAS authorizes, in a press release dated January 14, 2022, the administration of Janssen as a booster dose. “The Janssen vaccine can be offered to people over 55, even if they have received two doses of mRNA vaccines as a primary vaccination. Below 55, it can only be used as a booster only in exceptional circumstances, within the framework of a shared medical decision which provides clear information on the risks associated with this vaccine”, details the HAS.

What are the side effects of the booster shot?

A study published by the American health authorities in September 2021 showed that the side effects observed after a third booster dose of the anti-Covid vaccines from Pfizer and Moderna, were the same as for the 1st and 2nd dose. “Booster doses are well tolerated“, said Rochelle Walensky, director of the American CDC during a press conference. The frequency and type of side effects were similar to those seen after the second doses of vaccines, and they were mostly mild or moderate, and of short duration.” Among the side effects listed by the CDC (more than 268,000 participants):

  • Injection site reaction (for 79% of respondents): pain, redness, swelling
  • Fatigue (for 74%)
  • Headaches and muscle aches (for 55%)


– Opinion of the COVID-19 Scientific Council of November 20, 2021 – Terms of integration of the reminder / 3rd dose in the health pass

– Saciuk Y, et al. J Infect Dis. 202; 2:jiab556. Effectiveness of a third dose of BNT162b2 mRNA vaccine

– Barda N, et al. Lancet. 2021.29: S0140. Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study

– All you need to know about the vaccine booster against Covid-19. November 10, 2021.

– Press release from the High Authority for Health, August 24, 2021.

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